= BBMRI omics Hands-on Course = date: March 31, 2017 \\ Location: SURFsara, Utrecht \\ BBMRI url: https://www.bbmri.nl/event/bbmri-omics-introduction-and-hands-on-application/ \\ == Program == 10:00-10:30 Introduction to available omics data within BBMRI-omics.nl. Description of RNA-seq, 450k methylation, metabolomics, imputed genotypes, phenotypes and technical covariates. Data location and access. (Rick Jansen) 10.30-11.15: Introduction to the BBMRIomics R package for integrated analysis of BBMRI-omics data using R (Maarten van Iterson) 11.15-12.15: Practicum (Maarten van Iterson) 12.15-13.15: Lunch (demo: using BBMRI-Omics.nl online atlases (Jan-Bert van Klinken)) 13.15-13.45: Joost Verlouw: QTL lookup of GWAS hits. Take the SNP hits from a recent GWAS, extract corresponding BIOS genotype data, run association with full Methylation, Expression and Metabolomics data sets. 13.45-14.45: Practicum (Joost Verlouw) 14.45-15.15- Tea break 15:15-15:45: Introduction to the Brainshake 1H-NMR metabolomics platform (Marian Beekman) 15:45-16.30: Practicum. Analyzing Metabolomics data (Koen Dekker) 16:30-17:00: Allele specific expression (Niek de Klein & Freerk van Dijk) 17:00-17:45: Practicum (Niek de Klein & Freerk van Dijk)) 18:00 Drinks == Practicum guidelines and exercises == [http://bios-vm.bbmrirp3-lumc.surf-hosted.nl/BBMRIomics_HandsOn/BBMRIomics_Intro.html# Introduction to the BBMRIomics R package, Maarten van Iterson] \\ [aseWorkshop(1).2.pdf​]